Pick your class and the bosses you farm. Items that drop for every class are listed separately.

Class

AllBarbarianDruidNecromancerRogueSorcererSpiritbornPaladinWarlock

Boss

VarshanGrigoireLord ZirBeast in the IceUrivarDurielAndarielHarbinger of HatredThe ButcherAstarothBartuc

Varshan

Lair Key

Class-specific

100,000 StepsBarbarian

Ae'grom's SchismWarlock

Autumnal CrownDruid

Balazan's MaxtlatlSpiritborn

Death's PavaneRogue

EaglehornRogue

Greatstaff of the CroneDruid

Hangman's HandNecromancer

Levin GraspSorcerer

Onyx SoulSorcerer

OverkillBarbarian

Pitfighter's GullRogue

Raiment of the SeaSorcerer

Seal of the OphanimWarlock

Seal of the Second TrumpetPaladin

Shard of VerathielSorcerer, Druid, Barbarian, Rogue, Necromancer, Paladin, Warlock

Stone of VehemenDruid

The Hand of NazNecromancer

Thrice-Woven NightmareWarlock

Vox OmniumSorcerer

Wound DrinkerSpiritborn

Wreath of Auric LaurelPaladin

Grigoire

Lair Key

Class-specific

Bastion of Sir MatthiasPaladin

Cage of MadnessWarlock

DeathgripNecromancer

Desperate MarchRogue

Gohr's Devastating GripsBarbarian

Hands of the WorldbreakerWarlock

Hunter's ZenithDruid

Might of Qual-KehkBarbarian

Peacemonger's SignetSpiritborn

Seed of HorazonWarlock

Sire of SinWarlock

Strike of StormhornSorcerer

SunbrandPaladin

The BasiliskDruid

The MaestroRogue

The MortacruxNecromancer

Vision of the FirestormSorcerer

Will of StoneDruid

All classes

Paingorger's Gauntlets

Lord Zir

Lair Key

Class-specific

Cruor's EmbraceNecromancer

Dirge of OdiumWarlock

ElegyWarlock

Fang of the VipermagiSorcerer

Fields of CrimsonBarbarian

Fleshwrit CarapaceWarlock

Gathlen's BirthrightDruid

Judgment of AurielPaladin

Judicant's GlaivehelmPaladin

RimebloodSorcerer

Ring of the Midday HuntSpiritborn

Ring of Writhing MoonSpiritborn

Sanguivor, Blade of ZirNecromancer

Shroud of KhandurasRogue

SkyhunterRogue

Staff of Lam EsenSorcerer

The UmbracruxRogue

Twin StrikesBarbarian

Unsung Ascetic's WrapsDruid

Waxing GibbousDruid

X'Fal's Corroded SignetSorcerer, Druid, Barbarian, Rogue, Necromancer, Spiritborn, Warlock

Beast in the Ice

Class-specific

Accord of the WildsDruid

Airidah's Inexorable WillDruid

Deathless VisageNecromancer

Gift of FrostSorcerer

Hellhound's SabatonsWarlock

Howl from BelowNecromancer

Kabraxis' WillWarlock

Light's RebukePaladin

Malefic CrescentDruid

Orphan MakerRogue

Protection of the PrimeSpiritborn

Ring of the RavenousBarbarian

Saboteur's SignetRogue

Sanctis of KethamarPaladin

Scorn of the EarthSpiritborn

Starfall CoronetSorcerer

The Eightfold IdolWarlock

The Relentless HeartBarbarian

All classes

Signet of Pelghain

Urivar

Lair Key

Class-specific

Band of First BreathSpiritborn

Cassia's GraceRogue

Cathedral's SongPaladin

Cowl of Malefic TormentWarlock

Dark HowlDruid

Dolmen StoneDruid

FlamescarSorcerer

Gospel of the DevoteeNecromancer

Herald's MorningstarPaladin

Iceheart BraisSorcerer

Infernal HomunculusWarlock

Kilt of BlackwingDruid

Mantle of Mountain's FuryBarbarian

Molten BandSorcerer

Sunbird's GorgetSpiritborn

The Blade of Sight AflameWarlock

Unbroken ChainBarbarian

Will of RathmaNecromancer

WindforceRogue

Writhing Band of TrickeryRogue

All classes

Yen's Blessing

Duriel

Greater Lair Key

Class-specific

Bands of Ichorous RoseRogue

Blue RoseSorcerer

CondemnationRogue

Dark Stalker's MedallionBarbarian

Fractured RunestoneDruid

Galvanic AzuriteSorcerer

Gauntlets of SheolWarlock

Greenwalker's OathDruid

Mark of the Old WolfDruid

Mutilator PlateNecromancer

Path of Trag'OulNecromancer

Rictus of TerrorWarlock

Rod of KepelekeSpiritborn

Sabre of TsasgalBarbarian

Scourge of DurielWarlock

Sea Lord's Fine GlovesRogue

Staff of Endless RageSorcerer

SupplicationPaladin

The UndercrownNecromancer

Ward of the White DovePaladin

Widow's WebSpiritborn

Wushe Nak PaSpiritborn

All classes

Razorplate

Andariel

Greater Lair Key

Class-specific

Anathema of the PrimesWarlock

Ancients' OathBarbarian

Argent VeilPaladin

Assassin's StrideRogue

Craze of the Dead GodSpiritborn

DawnfirePaladin

Drognan's AnguishSorcerer

EbonpiercerNecromancer

Emblem of StaalbreakBarbarian

Esadora's Overflowing CameoSorcerer

Greenwalker's SignetDruid

HellhammerBarbarian

Insatiable FuryDruid

Jacinth ShellSpiritborn

Kessime's LegacyNecromancer

Lidless WallNecromancer

Night TerrorWarlock

OrsivaneSorcerer

Scepter of the ThreeWarlock

Storm's CompanionDruid

All classes

Godslayer Crown

Harbinger of Hatred

Greater Lair Key

Class-specific

Bane of Ahjad-DenBarbarian

Blood WakeNecromancer

Bridle of Tor'BaalosWarlock

Etna's Lost DaggerRogue

FlameweaverSorcerer

FleshrenderDruid

Gate of the Red DawnPaladin

Ifeh's Dire TotemDruid

Mantle of the GreyPaladin

Might of the UrsineDruid

Nomad's Longing HeartBarbarian

Pact of BoneNecromancer

Protean HeartSpiritborn

Scoundrel's LeathersRogue

SepazontecSpiritborn

Shrouded GiftRogue

Sidhe BindingsSorcerer

Spine of TathametWarlock

Tal Rasha's Iridescent LoopSorcerer

The Fecund SealWarlock

The Gloom WardNecromancer

Ugly Bastard HelmBarbarian

All classes

Temerity

The Butcher

Greater Lair Key

Class-specific

Chainscourged MailBarbarian

Cowl of the NamelessRogue

EmberfurySorcerer

Fist of the Iron RoseRogue

Fury of the WildsDruid

Heart of AzgarDruid

Hellbrand SignetWarlock

Hesha e KesungiSpiritborn

Lurid PactWarlock

Mace of King LeoricNecromancer

March of the Stalwart SoulPaladin

Moloch's Beating FlameWarlock

Nails of the Gore-CrownedWarlock

Path of the EmissarySpiritborn

Purified LightbringerDruid

Rage of HarrogathBarbarian

Ramaladni's Magnum OpusBarbarian

Red BlessingNecromancer

Red SermonPaladin

Ring of Red FurorBarbarian

Scoundrel's KissRogue

Shanar's ResonanceSorcerer

Staff of ZeraeSorcerer

The Butcher's CleaverDruid, Barbarian, Necromancer, Paladin, Warlock

Vengeful SinewNecromancer

Astaroth

Class-specific

Asheara's KhanjarRogue

Battle TranceBarbarian

Bindings of AttritionWarlock

Blood Moon BreechesNecromancer

Bloodless ScreamNecromancer

Bartuc

666 Burning Aether

Class-specific

ArcadiaPaladin

Arreat's BearingBarbarian

Axial ConduitSorcerer

AzurewrathSorcerer, Druid, Barbarian, Rogue, Necromancer, Paladin, Warlock

EarthbreakerDruid

Eye of BaalWarlock

Grasp of ShadowRogue

Gravewalker's HandNecromancer

Hand of ApotheosisWarlock

Harmony of EbewakaSpiritborn

Khamsin SteppewalkersDruid

Loyalty's MantleSpiritborn

MisericordeRogue

Mjölnic RyngDruid

Omen of PainNecromancer

Ophidian IrisSorcerer

Raiment of the InfiniteSorcerer

Sashes of the WretchedWarlock

Sundered NightPaladin

The Hemat StoneWarlock

The Open Eye of GorgorraBarbarian

The UnmakerNecromancer

Tuskhelm of Joritz the MightyBarbarian

Word of HakanRogue

All classes

Flickerstep

Mythic Uniques

Can drop from every lair boss

Ahavarion, Spear of Lycander

Andariel's Visage

Doombringer

El'Druin, Sword of Justice

Harlequin Crest

Heir of Perdition

Melted Heart of Selig

Nesekem, the Herald

Ring of Starless Skies

Shattered Vow

Shroud of False Death

The Grandfather

Tyrael's Might